The concomitant use of erythromycin with some of these drugs is contraindicated (see sections 4 ..
Skin and soft tissue infections boils and carbuncles, paronychia, abscesses, ustular acne, impetigo, cellulitis, erysipelas 7 ..
Protease inhibitors in concomitant administration of erythromycin and protease inhibitors, an inhibition of the decomposition of erythromycin has been observed ..
Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen ..
Pseudomembranous colitis has been rarely reported in association with erythromycin therapy (see section 4 ..
Oral antibiotics work best when there is a steady amount of the medication in the body ..
That means youll probably be using several different acne treatment medications at once. Cdad must be considered in all patients who present with diarrhoea following antibiotic use. There have been reports that erythromycin may aggravate the weakness of patients with myasthenia gravis.
Hepatic dysfunction including increased liver enzymes andor cholestatic hepatitis, with or without jaundice, has been infrequently reported with erythromycin. There have been reports that maternal macrolide antibiotics exposure within 7 weeks of delivery may be associated with a higher risk of infantile hypertrophic pylori stenosis (ihps) erythromycin is excreted in breast milk, therefore, caution should be exercised when erythromycin is administered to a lactating mothers due to reports of infantile hypertrophic pylori stenosis in breast-fed infants. Interaction with other medicinal products and other forms of interaction increases in serum concentrations of the following drugs metabolised by the cytochrome p450 system may occur when administered concurrently with erythromycin acenocoumarol, alfentanil, astemizole, bromocriptine, carbamazepine, cilostazol, cyclosporin, digoxin, dihydroergotamine, disopyramide, ergotamine, hexobarbitone, methylprednisolone, midazolam, omeprazole, phenytoin, quinidine, rifabutin, sildenafil, tacrolimus, terfenadine, domperidone, theophylline, triazolam, valproate, vinblastine and antifungals e.
Healthcare professionals are asked to report any suspected adverse reactions via the yellow card scheme at www. Oral anticoagulants there have been reports of increased anticoagulant effects when erythromycin and oral anticoagulants (e. Tell your dermatologist if your acne isnt improving at all, or if it gets better for a while but then returns.
In case of theophylline toxicity andor elevated serum theophylline levels, the dose of theophylline should be reduced while the patient is receiving concomitant erythromycin therapy. Age, weight and severity of the infection are important factors in determining the correct dosage. Note for younger children, infants and babies erythromycin ethylsuccinate suspensions, are normally recommended. There have been post-marketing reports of colchicine toxicity with concomitant use of erythromycin and colchicine. The induction decreases gradually during two weeks after discontinued treatment with cyp3a4 inducers.
And, compared to these other options, erythromycin simply isnt the most effective antibiotic treatment for acne. Healthcare professionals are asked to report any suspected adverse reactions via the yellow card scheme at www. Drugs that induce cyp3a4 (such as rifampicin, phenytoin, carbamazepine, phenobarbital, st johns wort) may induce the metabolism of erythromycin. Patients receiving erythromycin concurrently with drugs which can cause prolongation of the qt interval should be carefully monitored. Cimetidine may inhibit the metabolism of erythromycin which may lead to an increased plasma concentration.
Parents should be informed to contact their physician if vomiting or irritability with feeding occurs. Erythromycin use in patients who are receiving high doses of theophylline may be associated with an increase in serum theophylline levels and potential theophylline toxicity. As with other broad spectrum antibiotics, pseudomembranous colitis has been reported rarely with erythromycin. Treatment with antibacterial agents alters the normal flora of the colon, which may lead to overgrowth of c. Although erythromycin has been used for years to treat acne, its not the go-to acne treatment antibiotic that it used to be.
The recommended dose for infants and babies, for mild to moderate infections, is 500 mg daily in divided doses. Clostridium difficile-associated diarrhoea (cdad) has been reported with use of nearly all antibacterial agents including erythromycin, and may range in severity from mild diarrhoea to fatal colitis. . Oral erythromycin is not really meant to be used as a long-term acne treatment, though. Make sure you take the entire course prescribed, even if your acne clears up. Rare reports of rhabdomyolysis have been reported in patients taking these drugs concomitantly. To help combat antibiotic resistance, oral erythromycin shouldnt be the only treatment youre using to clear your acne. In one cohort of 157 newborns who were given erythromycin for pertussis prophylaxis, seven neonates (5) developed symptoms of non-bilious vomiting or irritability with feeding and were subsequently diagnosed as having ihps requiring surgical pyloromyotomy. It also can be used by younger children because, unlike some of the other oral antibiotics, it wont cause tooth discoloration. Oral erythromycin isnt the go-to acne treatment choice but, in certain cases, it can be helpful in getting acne under control.Feb 16, 2016 ... Erythromycin is a commonly prescribed antibiotic medicine used for bacteral infections and acne - trusted advice on its use, warnings and side ...